System Hot Keys

private SystemHotKeyListener _hotKeyListner = null;

private void Form1_Load(object sender, EventArgs e)
{
    // Initialize the SystemHotKeyListener.
    _hotKeyListner = new SystemHotKeyListener(this);

    // Attach the event processing procedure.
    _hotKeyListner.SystemHotKeyPressed += 
        new EventHandler<SystemHotKeyPressedEventArgs>(_hotKeyListner_SystemHotKeyPressed);

    // Create a hot key (Windows Logo key + Esc)
    HotKey testHotKey = new HotKey("TEST", KeyModifiers.Windows, Keys.Escape);

    // Register this hot key.
    _hotKeyListner.Register(testHotKey);
}

void _hotKeyListner_SystemHotKeyPressed(object sender, SystemHotKeyPressedEventArgs e)
{
    switch (e.HotKeyName)
    {
        case "TEST":
            MessageBox.Show("The Windows Logo + Esc key was pressed.");
            break;
    }
}